It occurred to me that there are very few Cursed-/Doomed-themed enemies, apart from their associated zones. Cursed is currently going through something of a revamp, so I've decided to draw mostly from Doomed talents. Here are a few of my ideas; most of them are harassers/support that you would want to take out quickly.
Sorrowbark
"A dead, twisted tree, with sickly greenish-black bark and thrashing branches." It has a great deal of health and armor, as well as a constant Gloom effect (with all the fixin's). Has infusions.
Mouthless Horror
"A mouthless humanoid, emaciated and hunch-backed. It seems to look upon you with pained, hungry eyes just before you begin to feel as though you are being devoured from within." Uses Feed, Devour Life, and Feed Power. Weak and cowardly, always keeping just within line-of-sight. Wears robes and carries a staff; these can be cursed.
Monolith
"A perfectly rectangular slab standing in the middle of the ground. At first, it seems unadorned; as you stare at it, characters and images seem to dance just out of sight. Perhaps if you could get a little closer..." The monolith uses Willful Strike, Unseen Force, and Arcane Bolts. It can also be inscribed with attack runes. Assuming Vaporize gets toned down, it would be another good candidate.
Gloomy FOO and Shade of FOO
These already exist in their respective zones; occasionally encountering them outside of their natural habitat would be a fun addition (though ego'ed enemies DOES threaten to get kind of bloaty).
Hysteric
"A totally unremarkable humanoid, aside from the incessant laughter, the foaming mouth, and the fact that it is crawling around on all fours. Probably because it is doubled-over with mania. The two knives it is holding in its manic grip could do some real damage with those spastic limbs." Hysterics would path like snakes (fast but winding), carry daggers (cursed), and use Agony (with the effects from Madness). Hateful Whisper is another possibility; it would only really be a threat to summoners, necromancers, and escort missions, but I suppose every class deserves its counter.
Gazic
"It's not clear what this eye came from, but you imagine it must be better off without it. Rolling sack-like across the ground, this deformed, callused, bleeding bag of vitreous ooze casts an unfocused glance at all who approach. It seems to see something that you can't." Creeping Darkness, Dark Vision, and Dark Torrent, of course. Primal Skin would also fit, though the player would never know. I thought the "floating" eyeball concept was just way too hackneyed.
Drifter
"You get the impression that this man doesn't belong here... that he doesn't belong anywhere. Perhaps you should keep your distance." Displace, Radiant Fear, Suppression, Flare, Piercing Shot. Attacks with a bow and wears light armor, all cursed. It'd be interesting if the Drifter was completely neutral until approached, though there is really no precedent for that.
New afflicted mobs
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New afflicted mobs
Sorry about all the parentheses (sometimes I like to clarify things).