ToME: the Tales of Maj'Eyal

Using Yeek's Dominant Will on an Acolyte of the Sect of Kryl-Feijan at the bottom of the Dark Crypt makes saving Melinda impossible. Once dominant will expires and the "friendly" acolyte dies killing the remaining acolytes does NOT stop the timer and Melinda will eventually be sacrificed by nothing. If you can't reproduce this try throwing inner demons somewhere in the mix.

Just lost a godlike NMRL Yeek thanks to this. Fun.

Well you actually just lost Melinda, then died trying to redo it.