ToME: the Tales of Maj'Eyal

Magical/Mental generics equivalent to the conditioning tree could be interesting. My brain's too frozen to think of details at the moment. A talent reducing hostile mental/magical durations (like vitality) & a way to use life as mana/psi (like adrenaline surge).

There's the mentalism tree, which features a very good status-clearing effect called "Mental Shielding." Instacast, clears up to (talent level rounded up) mental effects. Any charges left after activation stick around for six turns to block future effects.