Now I have done the back up bosses. Almost ready to start the Orcs properly. Need to make some decisions on equipment though. I might still not win but I am going to give my perspective from here.
I followed the basics of bpat (
viewtopic.php?f=59&t=46126) and found them to be very true. Matter Weaving, Reality Smearing, Web's of Fate, Energy Decomposition and 'Spin' makes your defence amazing. Induce Anomaly and Twist Fate do a good job of paradox control. Attenuate is a strong attack and also provides a decent HoT. Get those going, and supplement with the additional attacks (and Echoes from the Past is a good one) and you are good to go, you can almost forget about everything else including infusions. I was a bit lucky to get 3 Healing Lights so that has been all the healing I have needed.
I found that disintegrate was useful for positioning. I think it is also useful for removing enemies 'buffs'. Entropy also seems useful although I am not certain how necessary it has been (I am not playing on Insane).
I am not a good player, I tend to not be careful. So I used a shield rune most of the time to visually inform me if I saw enemies, I just recently got Stasis partially to get 1 in Time Shield so that I could free up that infusion slot (also to get Stop, supposedly another decently strong attack). I put 4 into Temporal Bolt so that I could get 2 cooldowns per enemy, I may end up regretting that if Stop is really great.
I also have only had it go off usefully once, but because I am a week player I have really appreciated Contingency and Time Stop.
I only have 16 more class points, I intend to put 1 more into Stop and then at least 3 into Empower, Extension and Matrix. Matrix is going to be on Seal Fate, Extension on Webs of Fate, and Empower on Attenuate.
If I don't get Hidden Resources I probably need Static History. It seems a bit 'gamey' to get Hidden Resources, but I should probably do it. I am also thinking about Cauterize because I am bad. That and a nice Heroism should really help me stay alive even after mistakes. I could have Heroism, Controlled Teleport, and a Wild (currently just Physical, I should get Physical/Mental). Or I could have Movement, Controlled Teleport, Wild?
I have enough to get an Artefact made for me. Should I do so before heading back East? Should I get the Ring of Dead? I don't have any Blood of Life.
What is obviously missing from my setup?
I have all these items I want one of my Rogue/Wyrmic/etc runs to have. I should drop it or just donate more (I have the game on Steam but not a 'donator' with Vault slots).