Pointers cause I apparently can't figure it out

[IvenGray]

1. About accuracy thing, I'm not really sure. Maybe it's just my personal habit to keep a higher accuracy, I put 2 or 3 points in Combat Accuracy and seldom need to worry about it. But it's OK if you don't miss most of the enemies. Some rogue rares do have a much higher defense than normal enemies. You can use Precise Strike to deal with them. It enables you to boost accuracy shortly, and would enable you to blindfight. That would be handy sometimes.

2. About Talents:

-Rush and Stunning Blows are very powerful. They are worth focusing.
-Sundering Armour & Sundering Arms are not worthy. At early stage, they merely do slightly more than normal attacks, IMO.
-Death Blow, Blood Frenzy and Adrenaline Surge are for late games.
-Bloodthirst Tree is incredibly good, you should unlock it.

3. What movement infusions do is to grant you a beneficial timed effect for 1 turn. So in the next game turn, your movement actions will only cost less than 0.2 game turn each time. But other actions (like activating sustainable talents) still cost about 1 game turn.

[TheFinn70]

I'd do the first level of each of the tier twos then go back and do the 2nd level of each, etc.

But a drawback is that you will have less exp in total.

I understand what you mean, but that's only true in theory.

In practice, I find it's very difficult to get experience in rogue-like mode once my life hits zero - if I can delay that from level 10 to level 15 or later, I'd say I'm making more total experience.

[The Revanchist]

Quite the contrary. A single point in Blurred Mortality makes gaining experience at 0 health way easier. Not so useful if you're a Bump class, but... Necromancers have it good there.

[eddparsons]

Last Hope often has movement infusions, along with some good regens.

I always visit there once I have ~60 gold as these can make a big difference in the early game.

If Last Hope doesn't have anything try Angolwen and the elf city (Shatur?)

Hmm... could be, though I don't have anything set that I'm aware of other than sustained stuff, would that kill it?
Which is to say, if I want to use movement infusions do I have to "turn off" everything that's already active and then use the infusion?

I wish the things were a little easier to come by so I could experiment more.