I would prefer a two coloumn display instead of the actual single coloumn, removing the [press 1] info that's quite obvious (perhaps it's better to put it in the pop-ups) since it's also on the left (except for the last two keys). This way you may check with a glance more talents.
This means 72 total talents instead of the actual 36. But I don't know about the hotkeys, since after plain key numbers, shifted and controlled... could be shift+ctrl for the fourth, alt for the fifth and alt+shift for the sixth.. Anyway I don't usually use key numbers, I prefer to click them.
However the twelve power jumps to the right and it's quite unaligned in 1024x768. I think it's better that goes down (so you can't see it in 1024x768) with an eventual two-coloumns configuration. I'd like the option to remove it, although it would be simple to render it useless hotkeying something irrelevant (that wouldn't show up if put down where cannot be seen in 1024x)... that because when I got a new power it goes in the next "open space" that could be the ugly unaligned confusing twelve slot

Some vertical line should be put between the two coloumns, to keep them distincted.