I'm currently running a level 46 Shaloren Berserker with Legacy of the Naloren and Stone Alchemy/Crafty hands. Legacy kills eventhough I got "only" 9/9 in exotic weapons mastery because of a (yet another) bug.
On the stone alchemy side of things, I gotta say I'm enjoying my four merchant super items

. And this is without farportals.
So yeah, stone alchemy is awesome especially in the endgame and so is legacy with maxxed exotic weapons mastery. I'd say this is a pretty strong combo in the endgame but you may need to delay your first prodigy for a few exp levels after 30 if you want legacy first. No biggie though. Also you need to be able to spare the generics which is not a problem for (not antimagic) bulwark or berserk.